2024

Tumor Immune Cell Targeting Chimeras (TICTACs) For Targeted Degradation of Macrophage-Associated Checkpoint Receptors

Morimoto, M.; Roberts, D. S.; Till, N. A.; Handy, E.; Bertozzi, C. R.*

Nature Chemical Biology, 2024, under revision.

Process Development of a Tricyclic Diazepine-based IDH1 Mutant Inhibitor

Maddess, M. L.*; Cleator, E.*; Morimoto, M.; Goodyear, A.; Dieguez-Vazquez, A.; Gibb, A.; Kirtley, A.; Christensen, M.; Song, C.; Peng, F.; Alam, M.; Kenn, S.; Oliver, S. F.

Organic Process Research & Development, 2024, 28 (6), pp 2343-2354. doi.org/10.1021/acs.oprd.4c00171

2023

Tumor Immune Cell Targeting Chimeras (TICTACs) For Targeted Depletion of Macrophage-Associated Checkpoint Receptors

Morimoto, M.; Till, N. A.; Bertozzi, C. R.*

bioRxiv, 2023, doi.org/10.1101/2023.12.06.570444

2022

Source of Rate Acceleration for Carbocation Cyclization in Biomimetic Supramolecular Cages

Nguyen, Q. N.†; Xia, K. T.†; Zhang, Y.†; Chen, N.†; Morimoto, M.†; Pei, X.; Ha, Y.; Guo, Y.; Yang, W.; Wang, L.; Bergman, R. G.; Raymond, K. N.; Toste, F.D.*; Tantillo. D. J.*

Journal of the American Chemical Society, 2022, 144 (25), pp 11413-11424. doi.org/10.1021/jacs.2c04179

Development of a Stereoselective Synthesis of (1R, 4R)- and (1S, 4S)-2-Oxa-5-azabicyclo[2,2,2]octane

Maddess, M. L.*; Cleator, E.*; Morimoto, M.; Goodyear, A.; Dieguez-Vazguez, A.; Gibb, A.; Kirtley, A.; Wang, J.; Qi, J.; Kong, L.; Alam, M.; Keen, S.; Oliver, S. F.; Wen, X.

Organic Process Research & Development, 2022, 26 (3), pp 640-647. doi.org/10.1021/acs.oprd.1c00098

2021

Chemoselective and Site-Selective Reductions Catalyzed by a Supramolecular Host and a Pyridine-Borane Cofactor

Morimoto, M.; Cao, W.; Bergman, R. G.; Raymond, K. N.; Toste, F. D.*

Journal of the American Chemical Society, 2021, 143 (4), pp 2108-2114. doi.org/10.1021/jacs.0c12479

2020

Advances in Supramolecular Host Mediated Reactivity

Morimoto, M.; Bierschenk, S. M.; Xia, K. T.; Bergman, R. G.; Raymond, K. N.; Toste, F. D.*

Nature Catalysis, 2020, 3, pp 969-984. doi.org/10.1038/s41929-020-00528-3

2019

Supramolecular Host-Selective Activation of Iodoarenes by Encapsulated Organometallics

Bender, T. A.†; Morimoto, M.†; Bierschenk, S. M.; Xia, K. T.; Bergman, R. G.; Raymond, K. N.; Toste, F. D.*

Journal of the American Chemical Society, 2019, 141 (4), pp 1701- 1706. doi.org/10.1021/jacs.8b11842

2018

Deconvoluting the Role of Charge in a Supramolecular Catalyst

Hong, C. M.†; Morimoto, M.†; Kapustin, E. A.; Alzakhem, N.; Bergman, R. G.; Raymond, K. N.; Toste, F. D.*

Journal of the American Chemical Society, 2018, 22 (7), pp 747- 754. doi.org/10.1021/jacs.8b01701

2017

Mechanism of Acylative Oxidation–Reduction–Condensation Reactions Using Benzoisothiazolones as Oxidant and Triethylphosphite as Stoichiometric Reductant

Gangireddy, P.; Patro, V. Lam, L.; Morimoto, M.; Liebeskind, L. S.*

Journal of Organic Chemistry, 2017, 82 (7), pp 3513–3529. doi.org/10.1021/acs.joc.7b00020